Nobel Prize in Chemistry: Trio of researchers distinguished for “ingenious methods to create new molecules”
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The Nobel Prize in Chemistry was today awarded to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for “the development of click chemistry and bioorthogonal chemistry”, or, in other words, for “the creation of ingenious methods to create new molecules “.

According to the Swedish Academy, “Laureates Barry Sharpless and Morten Meldal laid the groundwork for a functional form of chemistry – click chemistry – in which molecular building blocks fit together quickly and efficiently.”

“Click chemistry is used in the development of pharmaceuticals, to map DNA and create more suitable materials.”

Carolyn Bertozzi “has taken click chemistry to a new dimension, beginning to use it in living organisms. Its bioorthogonal reactions occur without interrupting the cell’s normal chemistry,” explains the Academy.

“Using bioorthogonal reactions, researchers have improved the functioning of cancer pharmaceuticals.”

The term ‘bioorthogonal’ chemistry refers to any chemical reaction that can occur within living systems without interfering with native biochemical processes. The term was coined by Carolyn R. Bertozzi in 2003.

American Barry Sharpless, 81, is the fifth person to win a second Nobel Prize, joining John Bardeen, Marie Skłodowska Curie, Linus Pauling and Frederick Sanger.

The announcement of the Chemistry award follows the one for Physics and Medicine.

The Nobel Prize in Physics 2022 was awarded yesterday to Alain Asqect, John F. Clauser and Anton Zeilinger for their work in quantum mechanics. The Nobel Prize in Medicine was awarded on Monday to Svante Pääbo from Sweden for his studies on human evolution.

In the coming days, the prizes for Literature, Peace and Economics will be announced.

The Nobel Prizes were born from the will of the Swedish scientist and industrialist Alfred Nobel (1833-1896) to bequeath a large part of his fortune to people who work for “a better world”. The international prestige of the Nobel prizes is largely due to the amounts awarded, which currently reach ten million Swedish kronor (more than 953,000 euros).

Source: With Agencies

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